Code | EK1536 |
Brand | Boster |
Title | Human Nectin-4/PVRL4 PicoKine"! ELISA Kit |
Description | Human Nectin-4/PVRL4 PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Nectin-4 |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1536 |
general_information | Nectin-4, also known as PVRL4, is an adhesion receptor of the immunoglobulin superfamily and functions in cell-cell adhesion. This gene is mapped to chromosome 1q23.3. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |
protein_id | Q96NY8 |
range_detection | 31.2pg/ml-2000pg/ml |
sensitivity | <10pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, serum, plasma(heparin, EDTA), cell lysates and urine. |
Target species | Hu |
Assay type | complete kit |