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CodeEK2065
BrandBoster
TitleHuman PLA2G4A PicoKine ELISA Kit
DescriptionHuman PLA2G4A PicoKine ELISA Kit
Size1 x 96T
alternative_nameCytosolic phospholipase A2
concentrationN/A
Scheda prodottoLINK
general_informationCytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. It is mapped to 1q31.1. This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca2+ levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
protein_idP47712
range_detection62.5pg/ml-4000pg/ml
sensitivity<50pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesHu
Target_igN/A
Assay typecomplete kit