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CodeEK1653
BrandBoster
TitleHuman Properdin PicoKine ELISA Kit
DescriptionHuman Properdin PicoKine ELISA Kit
Size1 x 96T
alternative_nameProperdin
concentrationN/A
Scheda prodottoLINK
general_informationProperdin or Factor P is the only known positive regulator of complement activation that stabilizes thealternative pathway convertases. This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.
protein_idP27918
range_detection312pg/ml-20000pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesHu
Target_igN/A
Assay typecomplete kit