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CodeEK1634
BrandBoster
TitleHuman Serpin A1/AAT PicoKine ELISA Kit
DescriptionHuman Serpin A1/AAT PicoKine ELISA Kit
Size1 x 96T
alternative_nameAlpha-1-antitrypsin
concentrationN/A
Scheda prodottoLINK
general_informationAlpha-1-antitrypsin or ± 1-antitrypsin (A1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene. The gene is located on the long arm of the fourteenth chromosome (14q32.1).The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.Like all serine protease inhibitors, A1AT has a characteristic secondary structure of beta sheets and alpha helices. Mutations in these areas can lead to non-functional proteins that can polymerise and accumulate in the liver(infantile hepatic cirrhosis).
protein_idP01009
range_detection1.56ng/ml-100ng/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesHu
Target_igN/A
Assay typecomplete kit