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CodeFEK1393
BrandBoster
TitleHuman Serpin C1/Antithrombin-III PicoKine™ Fast ELISA Kit
DescriptionHuman Serpin C1/Antithrombin-III PicoKine™ Fast ELISA Kit
Size1 x 96T
alternative_nameAntithrombin-III
concentrationN/A
Scheda prodottoLINK
general_informationAntithrombin III is the most important inhibitor of thrombin and other coagulation proteinases. It belongs to the serine proteinase inhibitor (serpin) superfamily of inhibitors and structurally related proteins, which contain reactive centers that have evolved to attract and entrap certain proteinases. Inherited antithrombin III deficiency (AT3D) is a risk factor for the early development of venous thromboembolism (THPH7). Antithrombin III regulates clot formation both by inhibiting thrombin activity directly and by interfering with earlier stages of the clotting cascade. By in situ hybridization and quantitative analysis of DNA dosage in carriers of chromosome 1 deletions, AT3 is mapped to 1q23-q25. The AT3 gene has 7 exons. It contains 9 complete and 1 partial repetitive ALU sequence elements, which occur in the introns of the gene at a higher frequency (about 22% of the intron sequence) than in the genome as a whole (about 5%).
protein_idP01008
range_detection312pg/ml-20,000pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target specieshuman
Target_igN/A
Assay typecomplete kit