Code | EK1404 |
Brand | Boster |
Title | Human Stanniocalcin 1/STC1 PicoKine"! ELISA Kit |
Description | Human Stanniocalcin 1/STC1 PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Stanniocalcin-1 |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1404 |
general_information | Stanniocalcin-1 is a glycoprotein which is encoded by the STC1 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. Hu Stanniocalcin-1 is a putative molecular biomarker of leukemic microenvironment and the only molecular function known up to date is a SUMO E3 ligase activity in the SUMOylation cycle. STC1 interacts with lots of proteins in the cytoplasm, mitochondria, endoplasmatic reticulum and dot-like fashion in the nucleus. The N-terminal region of STC1 is the function region which is responsible to establish the interaction with its partners, including SUMO1. Low resolution studies shows that STC1 is an anti-parallel homodimer in solution and the cystein 202 is responsible for the dimerization of this protein. All the 5 dissulfide bonds of human STC1 are conserved and have the same profile of fish STC. |
protein_id | P52823 |
range_detection | 31.2pg/ml-2000pg/ml |
sensitivity | <10pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Target species | Hu |
Assay type | complete kit |