| Code | EK0842 |
| Brand | Boster |
| Title | Human TNFSF11/RANKL PicoKine"! ELISA Kit |
| Description | Human TNFSF11/RANKL PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Tumor necrosis factor ligand superfamily member 11 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0842 |
| general_information | Receptor activator of nuclear factor kappa-B ligand(RANKL), also known as tumor necrosis factor ligand superfamily member 11(TNFSF11), is a protein that in humans is encoded by the TNFSF11 gene. This gene encodes a member of the tumor necrosis factor(TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This gene is mapped to chromosome13q14.11. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. This gene may play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. |
| protein_id | O14788 |
| range_detection | 78pg/ml-5000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
| Target species | Hu |
| Assay type | complete kit |
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