| Code | EK1686 |
| Brand | Boster |
| Title | Human ULBP3 PicoKine ELISA Kit |
| Description | Human ULBP3 PicoKine ELISA Kit |
| Size | 1 x 96T |
| alternative_name | UL16-binding protein 3 |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | UL16 binding protein 3 (ULBP3) is a cell surface glycoprotein encoded by ULBP3 gene located on the chromosome 6. It is mapped to 6q25.1. ULBP3 is related to MHC class I molecules, but its gene maps outside the MHC locus. The domain structure of ULBP3 differs significantly from those of conventional MHC class I molecules. It does not contain the ± 3 domain and the transmembrane segment. ULBP3 is thus composed of only the ± 1± 2 domain which is linked to the cell membrane by the GPI anchor. It functions as a stress-induced ligand for NKG2D receptor. The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics. |
| protein_id | Q9BZM4 |
| range_detection | 62.5pg/ml-4000pg/ml |
| sensitivity | <50pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | Hu |
| Target_ig | N/A |
| Assay type | complete kit |
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