Human Uromodulin/umod PicoKine ELISA Kit

Code	EK1690
Brand	Boster
Title	Human Uromodulin/umod PicoKine ELISA Kit
Description	Human Uromodulin/umod PicoKine ELISA Kit
Size	1 x 96T
alternative_name	Uromodulin
concentration	N/A
Scheda prodotto	LINK
general_information	The Tamm Horsfall glycoprotein (THP), also known as uromodulin, is a glycoprotein that in humans is encoded by the UMOD gene. The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
protein_id	P07911
range_detection	156pg/ml-10000pg/ml
sensitivity	<10pg/ml
storage	Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection method	ELISA
Sample Type	cell culture supernates, serum and plasma(heparin).
Target species	Hu
Target_ig	N/A
Assay type	complete kit