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CodeA05766
BrandBoster
TitleIKB beta Polyclonal Antibody
DescriptionIKB beta Polyclonal Antibody
Size100 ul
alternative_nameNF-kappa-B inhibitor beta
cloneN/A
concentrationN/A
Scheda prodottoLINK
formatN/A
general_informationNF-kappa-B inhibitor beta, also known as IKBB or TRIP9, is a protein that in humans is encoded by the NFKBIB gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. This gene is mapped to 19q13.2. It has been found that in vivo, NFKBIB serves both to inhibit and to facilitate the inflammatory response. NFKBIB degradation releases NF-kappa-B dimers, which upregulate proinflammatory target genes such as TNF-alpha. Surprisingly, absence of NFKBIB results in a dramatic reduction of TNF-alpha in response to lipopolysaccharide, even though activation of NF-kappa-B is normal.
hostRabbit
immunogenN/A
isotypeN/A
protein_idNFKBIB
purityN/A
storageAt -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
ApplicationWB
Target speciesHu
HostRabbit
ClassPolyclonal
LabeledUnconjugated