| Code | PB9496 |
| Brand | Boster |
| Title | ITCH/AIP4 Polyclonal Antibody |
| Description | ITCH/AIP4 Polyclonal Antibody |
| Size | 100 ug |
| alternative_name | AIF4 antibody|AIP4 antibody|Atrophin 1 interacting protein 4 antibody|Atrophin-1-interacting protein 4 antibody|dJ468O1.1 antibody|dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4)) antibody|dJ468O1.1 atrophin 1 interacting protein 4 AIP4 antibody|E3 ubiquitin protein ligase Itchy homolog antibody|E3 ubiquitin-protein ligase Itchy homolog antibody|EC 6.3.2 antibody|Itch antibody|ITCH_HUMAN antibody|Itchy E3 ubiquitin protein ligase antibody|Itchy E3 ubiquitin protein ligase homolog antibody|Itchy E3 ubiquitin protein ligase homolog mouse antibody|Itchy E3 ubiquitin protein ligase, mouse, homolog of antibody|itchy homolog E3 ubiquitin protein ligase antibody|Itchy mouse homolog E3 ubiquitin protein ligase antibody|NAPP1 antibody|NFE2 associated polypeptide 1 antibody| NFE2-associated polypeptide 1 antibody|Ubiquitin protein ligase ITCH antibody |
| clone | N/A |
| concentration | N/A |
| Scheda prodotto | LINK |
| format | Whole IgG |
| general_information | ITCH is an ubiquitin-conjugating enzyme. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| host | Rabbit |
| immunogen | A synthetic peptide corresponding to a sequence in the middle region of human ITCH/AIP4 (410-437aa AMQQFNQRFIYGNQDLFATSQSKEFDPL), different from the related mouse sequence by one amino acid. |
| isotype | IgG |
| Secondary antibodies | LINK |
| protein_id | Q96J02 |
| purity | Affinity purified |
| storage | At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing. |
| Application | WB |
| Target species | Hu |
| Host | Rabbit |
| Class | Polyclonal |
| Labeled | Unconjugated |
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