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CodePA1304
BrandBoster
TitleLPL Polyclonal Antibody
DescriptionLPL Polyclonal Antibody
Size100 ug
alternative_nameLipoprotein lipase(LPL)
cloneN/A
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationLipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. Lipoprotein lipase has been difficult to purify, and its protein sequence remained undetermined until it could be deduced from the nucleotide sequence of its cDNA. The gene encodes a protein of 475 amino acids that becomes a mature protein of 448 residues after cleavage of a signal peptide. Analysis of the sequence indicated that human lipoprotein lipase, hepatic lipase, and pancreatic lipase are members of a gene family. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion.
hostRabbit
id_area_ricerca26
immunogenA synthetic peptide corresponding to a sequence at the C-terminal of human LPL, different from the related mouse and rat sequences by two amino acids.
isotypeIgG
Secondary antibodiesLINK
protein_id_urlLINK
purityAffinity purified
research_areaObesity
storage"At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing. "
ApplicationWB
Target speciesHu, Ms, Rt, Bv.
HostRabbit
ClassPolyclonal
LabeledUnconjugated