Code | EK0658-PR |
Brand | Boster |
Title | Monkey primate APP PicoKine"! ELISA Kit |
Description | Monkey primate APP PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Amyloid beta A4 protein |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0658-PR |
general_information | Amyloid precursor protein(APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid(Abeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive. |
protein_id | P05067 |
range_detection | 312pg/ml-20,000pg/ml |
sensitivity | <100pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates,serum and plasma(heprain, EDTA) |
Target species | Monkey |
Assay type | complete kit |