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CodeEK0311-PR
BrandBoster
TitleMonkey primate BMP-2 PicoKine"! ELISA Kit
DescriptionMonkey primate BMP-2 PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameBone morphogenetic protein 2
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0311-PR
general_informationBone morphogenetic protein-2(BMP-2, BMP 2A) belongs to the transforming growth factor beta(TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins(BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant monkey primate BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.
protein_idC8C060
range_detection31.2pg/ml-2000pg/ml
sensitivity<2pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typebone tissue, cell culture supernates and serum.
Target speciesMonkey
Assay typecomplete kit