Code | EK1535 |
Brand | Boster |
Title | Mouse Artemin PicoKine"! ELISA Kit |
Description | Mouse Artemin PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Artemin |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1535 |
general_information | Artemin, also known as enovin or neublastin, is a protein that in humans is encoded by the ARTN gene. This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. |
protein_id | Q9Z0L2 |
range_detection | 31.2pg/ml-2000pg/ml |
sensitivity | <10pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, serum and plasma (heparin, EDTA). |
Target species | Mouse |
Assay type | complete kit |