| Code | EK1303 |
| Brand | Boster |
| Title | Mouse CD22/Siglec 2 PicoKine"! ELISA Kit |
| Description | Mouse CD22/Siglec 2 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | B-cell receptor CD22 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1303 |
| general_information | CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. This gene is mapped to 19q13.2. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. It is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signalling. This gene can downmodulate signaling through the IgM and IgD B-cell receptors(BCRs), but not through the IgG BCR, because the IgG cytoplasmic tail prevents CD22 phosphorylation and actually enhances IgG-BCR signaling. |
| protein_id | P35329 |
| range_detection | 156pg/ml-10,000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
| Target species | Mouse |
| Assay type | complete kit |
Attendere..
