| Code | EK1290 |
| Brand | Boster |
| Title | Mouse DMP-1 PicoKine"! ELISA Kit |
| Description | Mouse DMP-1 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Dentin matrix acidic phosphoprotein 1 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1290 |
| general_information | Dentin matrix acidic phosphorprotein 1 is a protein that in humans is encoded by the DMP1 gene. It belongs to the small integrin-binding ligand N-linked glycoprotein(SIBLING) family of secreted phosphoproteins. This gene is mapped to 4q22.1. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. In undifferentiated osteoblasts, DMP-1 is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation, the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. |
| protein_id | O55188 |
| range_detection | 156pg/ml-10,000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin, EDTA). |
| Target species | Mouse |
| Assay type | complete kit |
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