| Code | EK0336 |
| Brand | Boster |
| Title | Mouse FAS/Cd95 PicoKine"! ELISA Kit |
| Description | Mouse FAS/Cd95 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Tumor necrosis factor receptor superfamily member 6 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0336 |
| general_information | Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the nerve growth factor(NGF)/tumour necrosis factor(TNF) receptor superfamily and mediates apoptosis. The nucleotide sequence of the cDNAs reveales that the molecule coding for the Fas antigen determinant is a 319 amino acid polypeptide with a single transmembrane domain. The extracellular domain is rich in cysteine residue, and shows a similarity to that of human tumor necrosis factor receptors, human nerve growth factor receptor, and human B cell antigen CD40. The APO-1 antigen as defined by the mouse monoclonal antibody anti-APO-1 is previously found to be expressed on the cell surface of activated human T and B lymphocytes and a variety of malignant human lymphoid cell lines. The APO-1 antigen is found to be a membrane glycoprotein of 48-kDa. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. Fas can play a role as an inducer of both neurite growth in vitro and accelerates recovery after nerve injury in vivo. |
| protein_id | Q8C350 |
| range_detection | 31.2pg/ml-2000pg/ml |
| sensitivity | <3pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin, EDTA, citrate). |
| Target species | Mouse |
| Assay type | complete kit |
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