Code | EK0431 |
Brand | Boster |
Title | Mouse IL-17 PicoKine"! ELISA Kit |
Description | Mouse IL-17 PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Interleukin 17A |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0431 |
general_information | IL-17 is an inflammatory cytokine produced primarily by a unique lineage of CD4 T cells that plays critical roles in the pathogenesis of multiple autoimmune diseases. Interleukin-17 is expressed by activated T cells and is 57% identical to the 17- to 26-kD secretory glycoprotein encoded by gene 13 of the herpesvirus saimiri(HVS-13). IL17 induces nuclear factor kappa-B and the expression of IL6, intercellular adhesion molecule-1, granulocyte macrophage colony-stimulating factor,and prostaglandin E2, as well as the maturation of CD34 positive hematopoietic precursors into neutrophils. Anti-IL17 antibodies significantly inhibited osteoclast formation induced by culture media of RA synovial tissues. The standard product used in this kit is recombinant mouse IL-17, consisting of 137 amino acids with the molecular mass of 15.5KDa. |
protein_id | Q544E6 |
range_detection | 15.6pg/ml-1000pg/ml |
sensitivity | <1pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Target species | Mouse |
Assay type | complete kit |