| Code | EK1148 |
| Brand | Boster |
| Title | Mouse PCSK9/Proprotein Convertase 9 PicoKine"! ELISA Kit |
| Description | Mouse PCSK9/Proprotein Convertase 9 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Proprotein convertase subtilisin/kexin type 9 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1148 |
| general_information | Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons. |
| protein_id | Q80W65 |
| range_detection | 62.5pg/ml-4000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
| Target species | Mouse |
| Assay type | complete kit |
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