| Code | FEK1192 |
| Brand | Boster |
| Title | Mouse Progranulin PicoKine™ Fast ELISA Kit |
| Description | Mouse Progranulin PicoKine™ Fast ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Granulins |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | Granulin, also known as Proepithelin(PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. |
| protein_id | P28798 |
| range_detection | 0.78ng/ml-50ng/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | mouse |
| Target_ig | N/A |
| Assay type | complete kit |
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