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CodeEK0769
BrandBoster
TitleMouse TNFRSF18/GITR PicoKine"! ELISA Kit
DescriptionMouse TNFRSF18/GITR PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameTumor necrosis factor receptor superfamily member 18
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0769
general_informationTumor necrosis factor receptor superfamily member 18(TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. This gene is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
protein_idO35714
range_detection62.5pg/ml-4000pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Target speciesMouse
Assay typecomplete kit