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CodeMA1079
BrandBoster
TitlePan Cadherin   Monoclonal Antibody
DescriptionPan Cadherin   Monoclonal Antibody
Size100 ug
alternative_nameUVO
clonePC-79
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationCadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma.
hostMouse
immunogenSynthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with an extra N-terminal lysine residue (24 amino acids) coupled to KLH.
isotypeIgG1
Secondary antibodiesLINK
protein_idHu(P12830), Mouse(P09803), Rat(Q9R0T4), Hu(P19022), Mouse(P15116), Rat(Q9Z1Y3), Hu(P22223), Mouse(P10287), Rat(F1LMI3)
purityAffinity purified
storage"At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing. "
ApplicationWB, IHC-P
Target speciesHu, Ms, Rt,Rb, Ck, Rp
HostMouse
ClassMonoclonal
LabeledUnconjugated