| Code | MA1080 |
| Brand | Boster |
| Title | Paxillin Monoclonal Antibody |
| Description | Paxillin Monoclonal Antibody |
| Size | 100 ug |
| clone | PAX-14 |
| concentration | N/A |
| Scheda prodotto | LINK |
| format | Whole IgG |
| general_information | The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells. |
| host | Mouse |
| immunogen | C-terminal part of recombinant chicken paxillin (amino acids 305-559). |
| isotype | IgG1 |
| Secondary antibodies | LINK |
| protein_id | Hu(P49023), Mouse(Q8VI36), Rat(Q66H76) |
| purity | Affinity purified |
| storage | "At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time.
Avoid repeated freezing and thawing.
" |
| Application | WB, ICC |
| Target species | Hu, Ms, Rt, Ck |
| Host | Mouse |
| Class | Monoclonal |
| Labeled | Unconjugated |