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CodeMA1085
BrandBoster
TitlePKBAlpha Monoclonal Antibody
DescriptionPKBAlpha Monoclonal Antibody
Size100 ug
alternative_nameAKT
cloneIML-26
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationPKBAlphaalso knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.
hostMouse
immunogenSynthetic peptide corresponding to amino acids 461-477 of human PKBAlpha/Akt1.
isotypeIgG1
Secondary antibodiesLINK
protein_idHu(P31749), Mouse(P31750), Rat(P47196)
purityAffinity purified
storage"At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing. "
ApplicationWB
Target speciesHu, Ms, Rt, Ck
HostMouse
ClassMonoclonal
LabeledUnconjugated