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CodeFEK0363
BrandBoster
TitleRat GDNF PicoKine™ Fast ELISA Kit
DescriptionRat GDNF PicoKine™ Fast ELISA Kit
Size1 x 96T
alternative_nameGlial cell line-derived neurotrophic factor
concentrationN/A
Scheda prodottoLINK
general_informationGlial cell line-derived neurotrophic factor(GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures. GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system.3 GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons. GDNF lies on the short arm of human chromosome 5, at 5p13.1-p13.3 ability to promote dopamine uptake in midbrain cultures. The standard product used in this kit is recombinant rat GDNF, which is a dimmer composed of two chains with 134 amino acids.
protein_idA7UGJ1
range_detection31.2pg/ml-2000pg/ml
sensitivity<4pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesRat
Target_igN/A
Assay typecomplete kit