| Code | EK0971 |
| Brand | Boster |
| Title | Rat RAGE PicoKine"! ELISA Kit |
| Description | Rat RAGE PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Advanced glycosylation end product-specific receptor |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0971 |
| general_information | RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as ⬠S AGER⬠ñ. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B(NF-kappaB). |
| protein_id | Q63495 |
| range_detection | 78pg/ml-5,000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
| Target species | Rat |
| Assay type | complete kit |
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