| Code | FEK1281 |
| Brand | Boster |
| Title | Rat RANK PicoKine™ Fast ELISA Kit |
| Description | Rat RANK PicoKine™ Fast ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Protein Tnfrsf11a |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | Receptor Activator of Nuclear Factor κ B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is a recently described TNF receptor family member, and its ligand, RANKL, promote survival of dendritic cells and differentiation of osteoclasts. RANK contains 383 amino acids in its intracellular domain(residues 234-616), which contain three putative TRAF-binding domains(termed I, II, and III). RANK interacts with various TRAFs through distinct motifs and activates NF-kappaB via a novel TRAF6 interaction motif, which then activates NIK, thus leading to NF-kappaB activation, whereas RANK most likely activates JNK through a TRAF2-interacting region in RANK. The standard in this kit is recombinant human RANK with the sequence of Q29-G213 aa. It is a dipolymer which compose of two chains, and the molecular weight of each is 48kda. |
| protein_id | F1M8Z6 |
| range_detection | 62.5pg/ml-4000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | rat |
| Target_ig | N/A |
| Assay type | complete kit |
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