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CodeEK0982
BrandBoster
TitleRat TGF-Beta 2 PicoKine"! ELISA Kit
DescriptionRat TGF-Beta 2 PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameTransforming growth factor beta-2
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0982
general_informationTransforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured human anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.
protein_idQ07257
range_detection31.2pg/ml-2000pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin, EDTA, citrate).
Target speciesRat
Assay typecomplete kit